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The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function.
Johnson LR, Lee DY, Eacret JS, Ye D, June CH, Minn AJ. Johnson LR, et al. . Haider N, et al. J Clin Invest. 2021 Sep 10:151818. doi: 10.1172/JCI151818. Online ahead of print. J Clin Invest. 2021. PMID: 34506305 .
Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche.
He X, Smith SE, Chen S, Li H, Wu D, Meneses-Giles PI, Wang Y, Hembree M, Yi K, Zhao X, Guo F, Unruh JR, Maddera LE, Yu Z, Scott A, Perera A, Wang Y, Zhao C, Bae K, Box A, Haug JS, Tao F, Hu D, Hansen DM, Qian P, Saha S, Dixon D, Anant S, Zhang D, Lin EH, Sun W, Wiedemann LM, Li L. .
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Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing.
Xu X, Chemparathy A, Zeng L, Kempton HR, Shang S, Nakamura M, Qi LS. Xu X, et al. .

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