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A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: A potential drug target in IPF.

Schuliga M, Kanwal A, Read J, Blokland KEC, Burgess JK, Prêle CM, Mutsaers SE, Grainge C, Thomson C, James A, Bartlett NW, Knight DA. .

Ketone body β-hydroxybutyrate is an autophagy-dependent vasodilator.

McCarthy CG, Chakraborty S, Singh G, Yeoh BS, Schreckenberger ZJ, Singh A, Mell B, Bearss NR, Yang T, Cheng X, Vijay-Kumar M, Wenceslau CF, Joe B. .

516 . Zhang T, et al. Nat Genet. 2021 Sep;53(9):1348-1359. doi: 10.1038/s41588-021-00920-0. Epub 2021 Sep 6. Nat Genet. 2021. PMID: 34493867 .

Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype.

Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. .

. Zauche LH, et al. N Engl J Med. 2021 Sep 8:NEJMc2113891. doi: 10.1056/NEJMc2113891. Online ahead of print. N Engl J Med. 2021. PMID: 34496196 .