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The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function.
Johnson LR, Lee DY, Eacret JS, Ye D, June CH, Minn AJ. Johnson LR, et al. . Nature. 2021 Sep;597(7877):561-565. doi: 10.1038/s41586-021-03887-4. Epub 2021 Sep 8. Nature. 2021. PMID: 34497418
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The NF-κB transcriptional footprint is essential for SARS-CoV-2 replication.
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V, Blanco-Melo D, Panis M, Lim JK, Elemento O, Schwartz RE, Rosenberg BR, Chandwani R, tenOever BR. . Pruitt RN, et al. Nature. 2021 Sep 8. doi: 10.1038/s41586-021-03829-0. Online ahead of print. Nature. 2021. PMID: 34497423 .
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