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HCC subtypes based on the activity changes of immunologic and hallmark gene sets in tumor and nontumor tissues.

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Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche.

He X, Smith SE, Chen S, Li H, Wu D, Meneses-Giles PI, Wang Y, Hembree M, Yi K, Zhao X, Guo F, Unruh JR, Maddera LE, Yu Z, Scott A, Perera A, Wang Y, Zhao C, Bae K, Box A, Haug JS, Tao F, Hu D, Hansen DM, Qian P, Saha S, Dixon D, Anant S, Zhang D, Lin EH, Sun W, Wiedemann LM, Li L. . Delahoy MJ, et al. MMWR Morb Mortal Wkly Rep. 2021 Sep 10;70(36):1255-1260. doi: 10.15585/mmwr.mm7036e2. MMWR Morb Mortal Wkly Rep. 2021. PMID: 34499627 .

. Shah ASV, et al. N Engl J Med. 2021 Sep 8:NEJMc2106757. doi: 10.1056/NEJMc2106757. Online ahead of print. N Engl J Med. 2021. PMID: 34496200 . Siegel DA, et al. MMWR Morb Mortal Wkly Rep. 2021 Sep 10;70(36):1249-1254. doi: 10.15585/mmwr.mm7036e1. MMWR Morb Mortal Wkly Rep. 2021. PMID: 34499628 .

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