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Programmable RNA targeting with the single-protein CRISPR effector Cas7-11.
Özcan A, Krajeski R, Ioannidi E, Lee B, Gardner A, Makarova KS, Koonin EV, Abudayyeh OO, Gootenberg JS. .
. SenGupta T, et al. Cell Rep. 2021 Sep 7;36(10):109668. doi: 10.1016/j.celrep.2021.109668. Cell Rep. 2021. PMID: 34496255 . Wightman DP, et al. Nat Genet. 2021 Sep;53(9):1276-1282. doi: 10.1038/s41588-021-00921-z. Epub 2021 Sep 7. Nat Genet. 2021. PMID: 34493870 .
The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance autonomous and endogenous immune function.
Johnson LR, Lee DY, Eacret JS, Ye D, June CH, Minn AJ. Johnson LR, et al. .
Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial.
Marconi VC, Ramanan AV, de Bono S, Kartman CE, Krishnan V, Liao R, Piruzeli MLB, Goldman JD, Alatorre-Alexander J, de Cassia Pellegrini R, Estrada V, Som M, Cardoso A, Chakladar S, Crowe B, Reis P, Zhang X, Adams DH, Ely EW; COV-BARRIER Study Group. .
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